Juxtapapillary Retinal Capillary Hemangioma: New Therapeutic Strategies
Medical hypothesis discovery and innovation in ophthalmology,
Vol. 3 No. 3 (2014),
1 September 2014
,
Page 71-75
Abstract
The treatment of juxtapapillary retinal capillary hemangiomas (JRCHs) is still a therapeutic dilemma without established guidelines. Because of the location of these hemangiomas on or adjacent to the optic nerve, treatment is difficult and complex, especially when JRCHs are located in the papillomacular bundle. This manuscript reviews the clinically relevant data on literature regarding the treatment of JRCHs, focusing on novel combined therapies that have shown promising results in these lesions.References
McCabe CM, Flynn HW Jr, Shields CL, Shields JA, Regillo CD, McDonald HR, Berrocal MH, Gass JD, Mieler WF. Juxtapapillary capillary hemangiomas: clinical features and visual acuity outcome. Ophthalmology. 2000 Dec;107(12):2240-8. PMID: 11097604
Magee MA, Kroll AJ, Lou PL, Ryan EA. Retinal capillary hemangiomas and von Hippel-Lindau disease. Semin Ophthalmol. 2006 Jul-Sep;21(3):143-50. PMID: 16912012
Kuo MT, Kou HK, Kao ML, Tsai MH, Chen YJ, Lin SA. Retinal capillary hemangiomas: clinical manifestations and visual prognosis. Chang Gung Med J. 2002 Oct;25(10):672-82. PMID: 12518779
McDonald HR. Diagnostic and therapeutic challenges. Juxtapapillaryretina capillary hemangioma. Retina. 2003 Feb;23(1):86-91. PMID: 12652237
Milewski SA. Spontaneous regression of a capillary hemangiomaof the optic disc. Arch Ophthalmol. 2002 Aug;120(8):1100-1. PMID: 12149071
Garcia-Arumà J1, Sararols LH, Cavero L, Escalada F, Corcóstegui BF. Therapeutic options for capillary papillary hemangiomas. Ophthalmology. 2000 Jan;107(1):48-54. PMID: 10647718
Singh AD, Nouri M, Shields CL, Shields JA, Perez N. Treatment of retinal capillary hemangioma. Ophthalmology. 2002 Oct;109(10):1799-806. PMID: 12359597
Schmidt D, Natt E, Neumann HP. Long-term results of laser treatment for retinal angiomatosis in von Hippel–Lindau disease. Eur J Med Res. 2000 Feb 28;5(2):47-58. PMID: 10720563
Russo V, Stella A, Barone A, Scott IU, Noci ND. Ruthenium-106 brachytherapy and intravitreal bevacizumab for retinal capillary hemangioma. Int Ophthalmol. 2012 Feb;32(1):71-5. PMID: 22271068
Mochizuki Y, Noda Y, Enaida H, Hata Y, Ueno A, Yoshikawa H, Ishibashi T. Retinal capillary hemangioma managed by transpupillary thermotherapy. Retina. 2004 Dec;24(6):981-4. PMID: 15580006
Atebara NH. Retinal capillary hemangioma treated with verteporfin photodynamic therapy. Am J Ophthalmol. 2002 Nov;134(5):788-90. PMID: 12429270
Schmidt-Erfurth UM, Kusserow C, Barbazetto IA, Laqua H. Benefits and complications of photodynamic therapy of papillary capillary hemangiomas. Ophthalmology. 2002 Jul;109(7):1256-66. PMID: 12093647
Sachdeva R, Dadgostar H, Kaiser PK, Sears JE, Singh AD. Verteporfin photodynamic therapy of six eyes with retinal capillary haemangioma. Acta Ophthalmol. 2010 Dec;88(8):e334-40. PMID: 20946329
Papastefanou VP, Pilli S, Stinghe A, Lotery AJ, Cohen VM. Photodynamic therapy for retinal capillary hemangioma. Eye (Lond). 2013 Mar;27(3):438-42. PMID: 23288135
Ach T, Thiemeyer D, Hoeh AE, Schaal KB, Dithmar S. Intravitreal bevacizumab for retinal capillary haemangioma: longterm results. Acta Ophthalmol. 2010 Jun;88(4):e137-8. PMID: 19681788
Wong WT, Liang KJ, Hammel K, Coleman HR, Chew EY. Intravitreal ranibizumab therapy for retinal capillary hemangioblastoma related to von Hippel–Lindau disease. Ophthalmology. 2008 Nov;115(11):1957-64. PMID: 18789534
Chelala E, Dirani A, Fadlallah A. Intravitreal anti-VEGF injection for the treatment of progressive juxtapapillary retinal capillary hemangioma: a case report and mini review of the literature. Clin Ophthalmol. 2013;7:2143-6. PMID: 24204117
Ziemssen F, Voelker M, Inhoffen W, Bartz-Schmidt KU, Gelisken F. Combined treatment of a juxtapapillary retinal capillary haemangioma with intravitreal bevacizumab and photodynamic therapy. Eye (Lond). 2007 Aug;21(8):1125-6. PMID: 17545966
Mennel S, Meyer CH, Callizo J. Combined intravitreal anti-vascular endothelial growth factor (Avastin) and photodynamic therapy to treat retinal juxtapapillary capillary haemangioma. Acta Ophthalmol. 2010 Aug;88(5):610-3. PMID: 19222401
Fong AH, Li KK, Wong D. Intravitreal ranibizumab, photodynamic therapy, and vitreous surgery for the treatment of juxtapapillary retinal capillary hemangioma. Graefes Arch Clin Exp Ophthalmol. 2011 Apr;249(4):625-7. PMID: 20676670
Mariotti C, Giovannini A, Reibaldi M, Nicolai M, Saitta A. 25-Gauge Vitrectomy Combined with Half-Fluence Photodynamic Therapy for the Treatment of Juxtapapillary Retinal Capillary Hemangioma. Case Rep Ophthalmol. 2014 May 29;5(2):162-7. PMID: 24987366
Wong WT, Chew EY. Ocular von Hippel-Lindau disease: clinical update and emerging treatments. Curr Opin Ophthalmol. 2008 May;19(3):213-7. PMID: 18408496
Girmens JF, Erginay A, Massin P, Scigalla P, Gaudric A, Richard S. Treatment of von Hippel–Lindau retinal hemangioblastoma by the vascular endothelial growth factor receptor inhibitor SU5416 is more effective for associated macular edema than for hemangioblastomas. Am J Ophthalmol. 2003 Jul;136(1):194-6. PMID: 12834696
von Buelow M, Pape S, Hoerauf H. Systemic bevacizumab treatment of a juxtapapillary retinal haemangioma. Acta Ophthalmol Scand. 2007 Feb;85(1):114-6. PMID: 17244223
Aaberg TM Jr, Aaberg TM Sr, Martin DF, Gilman JP, Myles R. Three cases of large retinalcapillary haemangiomas treated with verteporfinand photodynamic therapy. Arch Ophthalmol. 2005 Mar;123(3):328-32. PMID: 15767474
Baba T, Kitahashi M, Kubota-Taniai M, Oshitari T, Yamamoto S. Subretinal hemorrhage after photodynamic therapy for juxtapapillary retinal capillary hemangioma. Case Rep Ophthalmol. 2011 Apr 22;2(1):134-9. PMID: 21589848
Chen Y, Liu H, Zhang K, Gao L. Massive exudative retinal detachment following photodynamic therapy forretinal hemangioma in von Hippel-Lindau Syndrome. Photodiagnosis Photodyn Ther. 2014 Jun;11(2):250-3. PMID: 24632330
Kreusel KM, Bechrakis NE, Neumann HP, Foerster MH. Pars plana vitrectomy for juxtapapillary capillary retinal angioma. Am J Ophthalmol. 2006 Mar;141(3):587-9. PMID: 16490522
Gaudric A, Krivosic V, Duguin G, Massin P, Giraud S, Richard S. Vitreoretinal surgery for severe retinal capillary hemangiomas in Von Hippel-Lindau disease. Ophthalmology. 2011 Jan;118(1):142-9. PMID: 20801520
Reibaldi M, Rizzo S, Avitabile T, Longo A, Toro MD, Viti F, Saitta A, Giovannini A, Mariotti C. Iatrogenic retinal breaks in 25-gauge vitrectomy under air compared with the standard 25-gauge system for macular diseases. Retina. 2014 Aug;34(8):1617-22. PMID: 24651259
Baba T, Kitahashi M, Kubota-Taniai M, Oshitari T, Yamamoto S. Subretinal hemorrhage after photodynamic therapy for juxtapapillary retinal capillary hemangioma. Case Rep Ophthalmol. 2011 Apr 22;2(1):134-9. PMID: 21589848
Chen Y, Liu H, Zhang K, Gao L. Massive exudative retinal detachment following photodynamic therapy forretinal hemangioma in von Hippel-Lindau Syndrome. Photodiagnosis Photodyn Ther. 2014 Jun;11(2):250-3. PMID: 24632330
Kreusel KM, Bechrakis NE, Neumann HP, Foerster MH. Pars plana vitrectomy for juxtapapillary capillary retinal angioma. Am J Ophthalmol. 2006 Mar;141(3):587-9. PMID: 16490522
Gaudric A, Krivosic V, Duguin G, Massin P, Giraud S, Richard S. Vitreoretinal surgery for severe retinal capillary hemangiomas in Von Hippel-Lindau disease. Ophthalmology. 2011 Jan;118(1):142-9. PMID: 20801520
Reibaldi M, Rizzo S, Avitabile T, Longo A, Toro MD, Viti F, Saitta A, Giovannini A, Mariotti C. Iatrogenic retinal breaks in 25-gauge vitrectomy under air compared with the standard 25-gauge system for macular diseases. Retina. 2014 Aug;34(8):1617-22. PMID: 24651259
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