Combined Argon Laser and Low Dose Acetylsalicylic acid in Treatment of Acute Central Serous Chorioretinopathy
Medical hypothesis discovery and innovation in ophthalmology,
Vol. 7 No. 3 (2018),
1 September 2018
,
Page 126-132
Abstract
This study was designed to evaluate the efficacy of low-dose of oral acetylsalicylic acid (aspirin) with focal argon laser for the treatment of acute central serous chorioretinopathy (CSCR). In this prospective case-control study, 40 Patients with acute CSCR were classified randomly to two groups; group A with no treatment as the control group and group B with argon Laser in focal treatment once, followed by aspirin, 100 mg per day orally, with follow up period of 12 months by evaluation of visual acuity, and by Optical Coherence Tomography (OCT) Â every three months for one year. Patients in second group treated with argon Laser and aspirin showed more clinically significant improvement in both visual acuity and OCT macular thickness by the end of follow up period when compared with the observational group. It was concluded that argon Laser with low-dose oral aspirin results in improvement of visual acuity and OCT macular thickness.
References
Liew G, Quin G, Gillies M, Fraser-Bell S. Central serous chorioretinopathy: a review of epidemiology and pathophysiology. Clin Exp Ophthalmol. 2013;41(2):201-14. doi: 10.1111/j.1442-9071.2012.0 2848.x pmid: 22788735
Nicholson B, Noble J, Forooghian F, Meyerle C. Central serous chorioretinopathy: update on pathophysiology and treatment. Surv Ophthalmol. 2013;58(2):103-26. doi: 10.1016/j.survophthal.2012.07.004 pmid: 23410 821
Gass JD. Photocoagulation treatment of idiopathic central serous choroidopathy. Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol. 1977;83(3 Pt 1):456-67. pmid: 888264
Yannuzzi LA. Type A behavior and central serous chorioretinopathy. Trans Am Ophthalmol Soc. 1986;84:799-845. pmid: 3590481
Gilbert CM, Owens SL, Smith PD, Fine SL. Long-term follow-up of central serous chorioretinopathy. Br J Ophthalmol. 1984;68(11):815-20. doi: 10.1136/bjo.68 .11.815 pmid: 6541945
Yannuzzi LA. Type-A behavior and central serous chorioretinopathy. Retina. 1987;7(2):111-31. doi: 10.1097/00006982-198700720-00009 pmid: 3306853
Yannuzzi LA, Freund KB, Goldbaum M, Scassellati-Sforzolini B, Guyer DR, Spaide RF, et al. Polypoidal choroidal vasculopathy masquerading as central serous chorioretinopathy. Ophthalmology. 2000;107(4):767-77. doi: 10.1016/S0161-6420(99)001 73-6 pmid: 10768341
Burumcek E, Mudun A, Karacorlu S, Arslan MO. Laser photocoagulation for persistent central serous retinopathy: results of long-term follow-up. Ophthalmology. 1997;104(4):616-22. doi: 10.1016/S 0161-6420(97)30262-0 pmid: 9111253
Yamada K, Hayasaka S, Setogawa T. Fluorescein-angiographic patterns in patients with central serous chorioretinopathy at the initial visit. Ophthalmologica. 1992;205(2):69-76. doi: 10.1159/000310315 pmid: 1475084
Montero JA, Ruiz-Moreno JM. Optical coherence tomography characterisation of idiopathic central serous chorioretinopathy. Br J Ophthalmol. 2005;89(5):562-4. doi: 10.1136/bjo.2004.049403 pmid: 15834085
Mitarai K, Gomi F, Tano Y. Three-dimensional optical coherence tomographic findings in central serous chorioretinopathy. Graefes Arch Clin Exp Ophthalmol. 2006;244(11):1415-20. doi: 10.1007/s00417-006-0277-7 pmid: 16596405
Fujimoto H, Gomi F, Wakabayashi T, Sawa M, Tsujikawa M, Tano Y. Morphologic changes in acute central serous chorioretinopathy evaluated by fourier-domain optical coherence tomography. Ophthalmology. 2008;115(9):1494-500, 500 e1-2. doi: 10.1016/j.ophtha.2008.01.021 pmid: 18394706
Imamura Y, Fujiwara T, Margolis R, Spaide RF. Enhanced depth imaging optical coherence tomography of the choroid in central serous chorioretinopathy. Retina. 2009;29(10):1469-73. doi: 10.1097/IAE.0b013e3181be0a83 pmid: 19898183
Sharma T, Shah N, Rao M, Gopal L, Shanmugam MP, Gopalakrishnan M, et al. Visual outcome after discontinuation of corticosteroids in atypical severe central serous chorioretinopathy. Ophthalmology. 2004;111(9):1708-14. doi: 10.1016/j.ophtha.2004.03. 025 pmid: 15350327
Daruich A, Matet A, Dirani A, Bousquet E, Zhao M, Farman N, et al. Central serous chorioretinopathy: Recent findings and new physiopathology hypothesis. Prog Retin Eye Res. 2015;48:82-118. doi: 10.1016/j.preteyeres.2015.05.003 pmid: 26026923
Lim JW, Kang SW, Kim YT, Chung SE, Lee SW. Comparative study of patients with central serous chorioretinopathy undergoing focal laser photocoagulation or photodynamic therapy. Br J Ophthalmol. 2011;95(4):514-7. doi: 10.1136/bjo.2010 .182121 pmid: 20644214
Leaver P, Williams C. Argon laser photocoagulation in the treatment of central serous retinopathy. Br J Ophthalmol. 1979;63(10):674-7. doi: 10.1136/bjo.63. 10.674 pmid: 574397
Caccavale A, Imparato M, Romanazzi F, Negri A, Porta A, Ferentini F. A new strategy of treatment with low-dosage acetyl salicylic acid in patients affected by central serous chorioretinopathy. Med Hypotheses. 2009;73(3):435-7. doi: 10.1016/j.mehy.2009.03.036 pmid: 19427737
Iijima H, Iida T, Murayama K, Imai M, Gohdo T. Plasminogen activator inhibitor 1 in central serous chorioretinopathy. Am J Ophthalmol. 1999;127(4):477-8. doi: 10.1016/S0002-9394(98)0037 8-X pmid: 10218712
Caccavale A, Romanazzi F, Imparato M, Negri A, Morano A, Ferentini F. Low-dose aspirin as treatment for central serous chorioretinopathy. Clin Ophthalmol. 2010;4:899-903. doi: 10.2147/OPTH.S12583 pmid: 20714368
Okushiba U, Takeda M. [Study of choroidal vascular lesions in central serous chorioretinopathy using indocyanine green angiography]. Nippon Ganka Gakkai Zasshi. 1997;101(1):74-82. pmid: 9028111
Marmor MF, Tan F. Central serous chorioretinopathy: bilateral multifocal electroretinographic abnormalities. Arch Ophthalmol. 1999;117(2):184-8. doi: 10.1001/archopht.117.2.184 pmid: 10037562
Abouammoh MA. Advances in the treatment of central serous chorioretinopathy. Saudi J Ophthalmol. 2015;29(4):278-86. doi: 10.1016/j.sjopt.2015.01.007 pmid: 26586979
Novak MA, Singerman LJ, Rice TA. Krypton and argon laser photocoagulation for central serous chorioretinopathy. Retina. 1987;7(3):162-9. doi: 10.1097/00006982-198700730-00005 pmid: 3423431
Mitsui Y, Matsubara M, Kanagawa M. [Xenon light-exposure as a treatment of central serous retinopathy (a preliminary report)]. Nihon Ganka Kiyo. 1969;20(3):291-4. pmid: 5815620
Slusher MM. Krypton red laser photocoagulation in selected cases of central serous chorioretinopathy. Retina. 1986;6(2):81-4. doi: 10.1097/00006982-198600620-00003 pmid: 3749625
Elsner H, Porksen E, Klatt C, Bunse A, Theisen-Kunde D, Brinkmann R, et al. Selective retina therapy in patients with central serous chorioretinopathy. Graefes Arch Clin Exp Ophthalmol. 2006;244(12):1638-45. doi: 10.1007/s00417-006-0368-5 pmid: 16758179
Gupta B, Elagouz M, McHugh D, Chong V, Sivaprasad S. Micropulse diode laser photocoagulation for central serous chorio-retinopathy. Clin Exp Ophthalmol. 2009;37(8):801-5. doi: 10.1111/j.1442-9071.2009.021 57.x pmid: 19878226
Kawamura R, Ideta H, Hori H, Yuki K, Uno T, Tanabe T, et al. Transpupillary thermotherapy for atypical central serous chorioretinopathy. Clin Ophthalmol. 2012;6:175-9. doi: 10.2147/OPTH.S28239 pmid: 22331 974
Shukla D, Kolluru C, Vignesh TP, Karthikprakash S, Kim R. Transpupillary thermotherapy for subfoveal leaks in central serous chorioretinopathy. Eye (Lond). 2008;22(1):100-6. doi: 10.1038/sj.eye.6702449 pmid: 16732205
Fok AC, Chan PP, Lam DS, Lai TY. Risk factors for recurrence of serous macular detachment in untreated patients with central serous chorioretinopathy. Ophthalmic Res. 2011;46(3):160-3. doi: 10.1159/000324599 pmid: 21389741
Spalter HF. Photocoagulation of central serous retinopathy. A preliminary report. Arch Ophthalmol. 1968;79(3):247-53. doi: 10.1001/archopht.1968.03 850040249005 pmid: 5689148
Forooghian F, Meleth AD, Cukras C, Chew EY, Wong WT, Meyerle CB. Finasteride for chronic central serous chorioretinopathy. Retina. 2011;31(4):766-71. doi: 10.1097/IAE.0b013e3181f04a35 pmid: 21273946
Lim JW, Ryu SJ, Shin MC. The effect of intravitreal bevacizumab in patients with acute central serous chorioretinopathy. Korean J Ophthalmol. 2010;24(3):155-8. doi: 10.3341/kjo.2010.24.3.155 pmid: 20532141
Meyerle CB, Freund KB, Bhatnagar P, Shah V, Yannuzzi LA. Ketoconazole in the treatment of chronic idiopathic central serous chorioretinopathy. Retina. 2007;27(7):943-6. doi: 10.1097/IAE.0b013e318050ca 69 pmid: 17891021
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