Medical hypothesis discovery and innovation in ophthalmology

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Vazirani J, Nair D, Shanbhag S, Wurity S, Ranjan A, Sangwan V. Limbal Stem Cell Deficiency-Demography and Underlying Causes. Am J Ophthalmol. 2018;188:99-103. doi: 10.1016/j.ajo.2018.01.020 pmid: 29378178

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Daya SM, Chan CC, Holland EJ, Members of The Cornea Society Ocular Surface Procedures Nomenclature C. Cornea Society nomenclature for ocular surface rehabilitative procedures. Cornea. 2011;30(10):1115-9. doi: 10.1097/ ICO.0b013e318207f135 pmid: 21642849

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Scocco C, Kwitko S, Rymer S, Marinho D, Bocaccio F, Lindenmeyer R. HLA-matched living-related conjunctival limbal allograft for bilateral ocular surface disorders: long-term results. Arq Bras Oftalmol. 2008;71(6):781-7. doi: 10. 1590/s0004-27492008000600003 pmid: 19169506

Daya SM, Ilari FACSL. Living related conjunctival limbal allograft for the treatment of stem cell deficiency. Ophthalmology. 2001;108(1):126-33. doi: 10.1016/s0161-6420(00)00475-9

Gomes JA, Santos MS, Ventura AS, Donato WB, Cunha MC, Hofling-Lima AL. Amniotic membrane with living related corneal limbal/conjunctival allograft for ocular surface reconstruction in Stevens-Johnson syndrome. Arch Ophthalmol. 2003;121(10):1369-74. doi: 10.1001/archopht. 121.10.1369 pmid: 14557171

Santos MS, Gomes JA, Hofling-Lima AL, Rizzo LV, Romano AC, Belfort R, Jr. Survival analysis of conjunctival limbal grafts and amniotic membrane transplantation in eyes with total limbal stem cell deficiency. Am J Ophthalmol. 2005; 140(2):223-30. doi: 10.1016/j.ajo.2005.03.022 pmid: 16023069

Javadi MA, Baradaran-Rafii A. Living-related conjunctival-limbal allograft for chronic or delayed-onset mustard gas keratopathy. Cornea. 2009;28(1):51-7. doi: 10.1097/ICO. 0b013e3181852673 pmid: 19092406

Barreiro TP, Santos MS, Vieira AC, de Nadai Barros J, Hazarbassanov RM, Gomes JA. Comparative study of conjunctival limbal transplantation not associated with the use of amniotic membrane transplantation for treatment of total limbal deficiency secondary to chemical injury. Cornea. 2014;33(7):716-20. doi: 10.1097/ICO.0000000000000139 pmid: 24831198

Tsubota K, Shimmura S, Shinozaki N, Holland EJ, Shimazaki J. Clinical application of living-related conjunctival-limbal allograft. Am J Ophthalmol. 2002;133(1):134-5. doi: 10. 1016/s0002-9394(01)01208-9 pmid: 11755849

Sangwan VS, Matalia HP, Vemuganti GK, Ifthekar G, Fatima A, Singh S, et al. Early results of penetrating keratoplasty after cultivated limbal epithelium transplantation. Arch Ophthalmol. 2005;123(3):334-40. doi: 10.1001/archopht. 123.3.334 pmid: 15767475

Welder JD, Pandya HK, Nassiri N, Djalilian AR. Conjunctival limbal autograft and allograft transplantation using fibrin glue. Ophthalmic Surg Lasers Imaging. 2012;43(4):323-7. doi: 10.3928/15428877-20120618-04 pmid: 22788584

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Shimazaki J, Shimmura S, Tsubota K. Donor source affects the outcome of ocular surface reconstruction in chemical or thermal burns of the cornea. Ophthalmology. 2004; 111(1):38-44. doi: 10.1016/j.ophtha.2003.02.003 pmid: 14711712

Daya SM, Bell RW, Habib NE, Powell-Richards A, Dua HS. Clinical and pathologic findings in human keratolimbal allograft rejection. Cornea. 2000;19(4):443-50. doi: 10.1097/ 00003226-200007000-00007 pmid: 10928754

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Holland EJ. Epithelial transplantation for the management of severe ocular surface disease. Transactions of the American Ophthalmological Society. 1996;94:677.

Tsubota K, Toda I, Saito H, Shinozaki N, Shimazaki J. Reconstruction of the corneal epithelium by limbal allograft transplantation for severe ocular surface disorders. Ophthalmology. 1995;102(10):1486-96. doi: 10.1016/s0161-6420(95)30841-x pmid: 9097796

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Parihar JKS, Parihar AS, Jain VK, Kaushik J, Nath P. Allogenic cultivated limbal stem cell transplantation versus cadaveric keratolimbal allograft in ocular surface disorder: 1-year outcome. Int Ophthalmol. 2017;37(6):1323-31. doi: 10. 1007/s10792-016-0415-0 pmid: 28025793

Ilari L, Daya SM. Long-term outcomes of keratolimbal allograft for the treatment of severe ocular surface disorders. Ophthalmology. 2002;109(7):1278-84. doi: 10. 1016/s0161-6420(02)01081-3 pmid: 12093650

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Maruyama-Hosoi F, Shimazaki J, Shimmura S, Tsubota K. Changes observed in keratolimbal allograft. Cornea. 2006; 25(4):377-82. doi: 10.1097/01.ico.0000176608.65708.27 pmid: 16670472

Shimazaki J, Shimmura S, Fujishima H, Tsubota K. Association of preoperative tear function with surgical outcome in severe Stevens-Johnson syndrome. Ophthalmology. 2000; 107(8):1518-23. doi: 10.1016/s0161-6420(00)00214-1 pmid: 10919901

Shi W, Gao H, Wang T, Xie L. Combined penetrating keratoplasty and keratolimbal allograft transplantation in comparison with corneoscleral transplantation in the treatment of severe eye burns. Clin Exp Ophthalmol. 2008; 36(6):501-7. doi: 10.1111/j.1442-9071.2008.01802.x pmid: 18954310

Shimazaki J, Maruyama F, Shimmura S, Fujishima H, Tsubota K. Immunologic rejection of the central graft after limbal allograft transplantation combined with penetrating keratoplasty. Cornea. 2001;20(2):149-52. doi: 10.1097/ 00003226-200103000-00006 pmid: 11248817

Dua HS, Azuara-Blanco A. Allo-limbal transplantation in patients with limbal stem cell deficiency. Br J Ophthalmol. 1999; 83(4):414-9. doi: 10.1136/bjo.83.4.414 pmid: 10434862

Henderson TR, Coster DJ, Williams KA. The long term outcome of limbal allografts: the search for surviving cells. Br J Ophthalmol. 2001;85(5):604-9. doi: 10.1136/bjo.85.5.604 pmid: 11316725

Holland EJ, Djalilian AR, Schwartz GS. Management of aniridic keratopathy with keratolimbal allograft: a limbal stem cell transplantation technique. Ophthalmology. 2003; 110(1):125-30. doi: 10.1016/s0161-6420(02)01451-3 pmid: 12511357

Shen C, Chan CC, Holland EJ. Limbal Stem Cell Transplantation for Soft Contact Lens Wear-Related Limbal Stem Cell Deficiency. Am J Ophthalmol. 2015;160(6):1142-9 e1. doi: 10.1016/j.ajo.2015.07.038 pmid: 26299533

Movahedan A, Genereux BM, Darvish-Zargar M, Shah KJ, Holland EJ. Long-term management of severe ocular surface injury due to methamphetamine production accidents. Cornea. 2015;34(4):433-7. doi: 10.1097/ICO.00000000 00000364 pmid: 25642642

Ang AY, Chan CC, Biber JM, Holland EJ. Ocular surface stem cell transplantation rejection: incidence, characteristics, and outcomes. Cornea. 2013;32(3):229-36. doi: 10.1097/ICO. 0b013e318255eac4 pmid: 22668584

Liang L, Sheha H, Tseng SC. Long-term outcomes of keratolimbal allograft for total limbal stem cell deficiency using combined immunosuppressive agents and correction of ocular surface deficits. Arch Ophthalmol. 2009; 127(11):1428-34. doi: 10.1001/archophthalmol.2009.263 pmid: 19901207

Jafarinasab MR, Feizi S, Javadi MA, Karimian F, Soroush MR. Lamellar keratoplasty and keratolimbal allograft for mustard gas keratitis. Am J Ophthalmol. 2011;152(6):925-32 e2. doi: 10.1016/j.ajo.2011.05.018 pmid: 21871601

Javadi MA, Jafarinasab MR, Feizi S, Karimian F, Negahban K. Management of mustard gas-induced limbal stem cell deficiency and keratitis. Ophthalmology. 2011;118(7):1272-81. doi: 10.1016/j.ophtha.2010.11.012 pmid: 21397949

Biber JM, Skeens HM, Neff KD, Holland EJ. The cincinnati procedure: technique and outcomes of combined living-related conjunctival limbal allografts and keratolimbal allografts in severe ocular surface failure. Cornea. 2011; 30(7):765-71. doi: 10.1097/ICO.0b013e318201467c pmid: 21325942

Chan CC, Biber JM, Holland EJ. The modified Cincinnati procedure: combined conjunctival limbal autografts and keratolimbal allografts for severe unilateral ocular surface failure. Cornea. 2012;31(11):1264-72. doi: 10.1097/ICO. 0b013e31823f8e95 pmid: 22406944

Han ES, Wee WR, Lee JH, Kim MK. Long-term outcome and prognostic factor analysis for keratolimbal allografts. Graefes Arch Clin Exp Ophthalmol. 2011;249(11):1697-704. doi: 10.1007/s00417-011-1760-3 pmid: 21837442

Squissato V, Schiff J, Chan CC. Intravenous immunoglobulin for antibody-mediated keratolimbal allograft rejection. BMJ Case Rep. 2015;2015. doi: 10.1136/bcr-2015-210733 pmid: 26113596

Krakauer M, Welder JD, Pandya HK, Nassiri N, Djalilian AR. Adverse effects of systemic immunosuppression in keratolimbal allograft. J Ophthalmol. 2012;2012:576712. doi: 10.1155/2012/576712 pmid: 22523651

Baradaran-Rafii A, Eslani M, Djalillian AR. Complications of keratolimbal allograft surgery. Cornea. 2013;32(5):561-6. doi: 10.1097/ICO.0b013e31826215eb pmid: 23073489

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Kinoshita S, Koizumi N, Nakamura T. Transplantable cultivated mucosal epithelial sheet for ocular surface reconstruction. Exp Eye Res. 2004;78(3):483-91. doi: 10.1016/j.exer.2003.09.004 pmid: 15106927

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Koizumi N, Inatomi T, Suzuki T, Sotozono C, Kinoshita S. Cultivated corneal epithelial stem cell transplantation in ocular surface disorders11The authors have no financial interest in this work. Ophthalmology. 2001;108(9):1569-74. doi: 10.1016/s0161-6420(01)00694-7

Koizumi N, Inatomi T, Suzuki T, Sotozono C, Kinoshita S. Cultivated corneal epithelial transplantation for ocular surface reconstruction in acute phase of Stevens-Johnson syndrome. Arch Ophthalmol. 2001;119(2):298-300. pmid: 11176998

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Nakamura T, Sotozono C, Bentley AJ, Mano S, Inatomi T, Koizumi N, et al. Long-term phenotypic study after allogeneic cultivated corneal limbal epithelial transplantation for severe ocular surface diseases. Ophthalmology. 2010;117(12):2247-54 e1. doi: 10.1016/j.ophtha.2010.04. 003 pmid: 20673588

Pauklin M, Fuchsluger TA, Westekemper H, Steuhl KP, Meller D. Midterm results of cultivated autologous and allogeneic limbal epithelial transplantation in limbal stem cell deficiency. Dev Ophthalmol. 2010;45:57-70. doi: 10.1159/ 000315020 pmid: 20502027

Sangwan VS, Basu S, MacNeil S, Balasubramanian D. Simple limbal epithelial transplantation (SLET): a novel surgical technique for the treatment of unilateral limbal stem cell deficiency. Br J Ophthalmol. 2012;96(7):931-4. doi: 10.1136/ bjophthalmol-2011-301164 pmid: 22328817

Basu S, Sureka SP, Shanbhag SS, Kethiri AR, Singh V, Sangwan VS. Simple Limbal Epithelial Transplantation: Long-Term Clinical Outcomes in 125 Cases of Unilateral Chronic Ocular Surface Burns. Ophthalmology. 2016;123(5):1000-10. doi: 10.1016/j.ophtha.2015.12.042 pmid: 26896125

Bhalekar S, Basu S, Sangwan VS. Successful management of immunological rejection following allogeneic simple limbal epithelial transplantation (SLET) for bilateral ocular burns. BMJ Case Rep. 2013;2013. doi: 10.1136/bcr-2013-009051 pmid: 23505089

Iyer G, Srinivasan B, Agarwal S, Tarigopula A. Outcome of allo simple limbal epithelial transplantation (alloSLET) in the early stage of ocular chemical injury. Br J Ophthalmol. 2017; 101(6):828-33. doi: 10.1136/bjophthalmol-2016-309045 pmid: 28407620