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Initial Results From a New Model of Posterior Chamber Implantable Phakic Contact Lens: IPCL V2.0.

German Roberto BIANCHI


The aim of this study was to evaluate the corneal safety, intraocular pressure (IOP), vault and refractive efficiency of the new implantable phakic contact lens, IPCL V2.0 (Care Group, India). A prospective case series study was performed to evaluate 100 consecutive surgeries with IPCL V2.0 (spherical and toric models). Refractive results, corneal endothelial cell density (CD) and central corneal thickness (CCT) were measured at baseline and 6 months after surgery. Intraocular pressure was measured at baseline, 1 day and 6 months, and vault, 3 and 6 months after surgery. Surgical complications and cataract development were also evaluated. The mean corneal endothelial CD decreased by 2.9% with a statistically significance difference (p: 0.03). The mean CCT decreased by 0.87% at 6 months postoperative, without a statistical significance difference (p: 0.35). The mean ± standard deviation (SD) of IOP at baseline was 13.72 ±1.4 mm Hg, at 1 day postoperative was 13.88 ±1.2 mm Hg, and at 6 months was 13.62 ±1.3 mm Hg. These differences were not statistically significant (p: 0.37). The difference in vault between 3 and 6 months after surgery was not statistically significant (p: 0.97). The coefficient of correlation between the attempted versus achieved spherical equivalent (SE) change was R2: 0.958. Postoperative SE was between -0.50 D to 0.50 D in 52% of cases. The remaining of the eyes had SE values ranging from -1.5 D to +1.35 D. No intra or postoperative complications occurred and specifically cataract was not developed. The corneal endothelial CD, CCT, vault and IOP remained stable 6 months after surgery. Refraction was improved and the IPCL V 2.0 was implanted safely.


Munnerlyn CR, Koons SJ, Marshall J. Photorefractive keratectomy: a technique for laser refractive surgery. J Cataract Refract Surg. 1988;14(1):46-52. pmid: 3339547

Pallikaris IG, Papatzanaki ME, Stathi EZ, Frenschock O, Georgiadis A. Laser in situ keratomileusis. Lasers Surg Med. 1990;10(5):463-8. pmid: 2233101

Barraquer JI. Basis of refractive keratoplasty--1967. Refract Corneal Surg. 1989;5(3):179-93. pmid: 2488804

Bryant MR, Szerenyi K, Schmotzer H, McDonnell PJ. Corneal tensile strength in fully healed radial keratotomy wounds. Invest Ophthalmol Vis Sci. 1994;35(7):3022-31. pmid: 8206719

Choi DM, Thompson RW, Jr., Price FW, Jr. Incisional refractive surgery. Curr Opin Ophthalmol. 2002;13(4):237-41. pmid: 12165707

Roberts C. The cornea is not a piece of plastic. J Refract Surg. 2000;16(4):407-13.

Torres RM, Merayo-Lloves J, Jaramillo MA, Galvis V. [Corneal biomechanics]. Arch Soc Esp Oftalmol. 2005;80(4):215-23. pmid: 15852162

Marcos S. Aberrations and visual performance following standard laser vision correction. J Refract Surg. 2001;17(5):S596-601. pmid: 11583239

Marcos S, Barbero S, Llorente L, Merayo-Lloves J. Optical response to LASIK surgery for myopia from total and corneal aberration measurements. Invest Ophthalmol Vis Sci. 2001;42(13):3349-56. pmid: 11726644

Roberts CJ, Dupps WJ, Jr. Biomechanics of corneal ectasia and biomechanical treatments. J Cataract Refract Surg. 2014;40(6):991-8. doi: 10.1016/j.jcrs.2014.04.013 pmid: 24774009

Fatseas G, Stapleton F, Versace P. Role of percent peripheral tissue ablated on refractive outcomes following hyperopic LASIK. PLoS One. 2017;12(2):e0170559. doi: 10.1371/journal.pone.0170559 pmid: 28151939

Moller-Pedersen T, Cavanagh HD, Petroll WM, Jester JV. Stromal wound healing explains refractive instability and haze development after photorefractive keratectomy: a 1-year confocal microscopic study. Ophthalmology. 2000;107(7):1235-45. pmid: 10889092

Nettune GR, Pflugfelder SC. Post-LASIK tear dysfunction and dysesthesia. Ocul Surf. 2010;8(3):135-45. pmid: 20712970

Garcia-Zalisnak D, Nash D, Yeu E. Ocular surface diseases and corneal refractive surgery. Curr Opin Ophthalmol. 2014;25(4):264-9. doi: 10.1097/ICU.0000000000000077 pmid: 24865172

Pineda R, 2nd, Chauhan T. Phakic Intraocular Lenses and their Special Indications. J Ophthalmic Vis Res. 2016;11(4):422-8. doi: 10.4103/2008-322X.194140 pmid: 27994811

Perez-Cambrodi RJ, Pinero DP, Ferrer-Blasco T, Cervino A, Brautaset R. The posterior chamber phakic refractive lens (PRL): a review. Eye (Lond). 2013;27(1):14-21. doi: 10.1038/eye.2012.235 pmid: 23222559

Gomez-Bastar A, Jaimes M, Graue-Hernandez EO, Ramirez-Luquin T, Ramirez-Miranda A, Navas A. Long-term refractive outcomes of posterior chamber phakic (spheric and toric implantable collamer lens) intraocular lens implantation. Int Ophthalmol. 2014;34(3):583-90. doi: 10.1007/s10792-013-9860-1 pmid: 24114502

Al Sabaani N, Al Assiri A, Al Torbak A, Al Motawa S. Outcome of posterior chamber phakic intraocular lens procedure to correct myopia. Saudi J Ophthalmol. 2013;27(4):259-66. doi: 10.1016/j.sjopt.2013.06.009 pmid: 24371421

Stulting RD, John ME, Maloney RK, Assil KK, Arrowsmith PN, Thompson VM, et al. Three-year results of Artisan/Verisyse phakic intraocular lens implantation. Results of the United States Food And Drug Administration clinical trial. Ophthalmology. 2008;115(3):464-72 e1. doi: 10.1016/j.ophtha.2007.08.039 pmid: 18031820

Sanders DR, Doney K, Poco M, Group ICLiToMS. United States Food and Drug Administration clinical trial of the Implantable Collamer Lens (ICL) for moderate to high myopia: three-year follow-up. Ophthalmology. 2004;111(9):1683-92. doi: 10.1016/j.ophtha.2004.03.026 pmid: 15350323

Bredow L, Biermann J, Tomalla M, Schilgen G, Grossmann W, Reinhard T. Pilot study of a new posterior chamber phakic intraocular lens (epi.lens) for high myopia. J Refract Surg. 2011;27(12):858-62. doi: 10.3928/1081597X-20111017-01 pmid: 22045073

Mastropasqua L, Toto L, Nubile M, Falconio G, Ciancaglini M. Long-term complications of bilateral posterior chamber phakic intraocular lens implantation. J Cataract Refract Surg. 2004;30(4):901-4. doi: 10.1016/j.jcrs.2003.08.012 pmid: 15093658

Menezo JL, Peris-Martinez C, Cisneros-Lanuza AL, Martinez-Costa R. Rate of cataract formation in 343 highly myopic eyes after implantation of three types of phakic intraocular lenses. J Refract Surg. 2004;20(4):317-24. pmid: 15307392

Fernandes P, Gonzalez-Meijome JM, Madrid-Costa D, Ferrer-Blasco T, Jorge J, Montes-Mico R. Implantable collamer posterior chamber intraocular lenses: a review of potential complications. J Refract Surg. 2011;27(10):765-76. doi: 10.3928/1081597X-20110617-01 pmid: 21710954

Vasavada V, Srivastava S, Vasavada SA, Sudhalkar A, Vasavada AR, Vasavada VA. Safety and Efficacy of a New Phakic Posterior Chamber IOL for Correction of Myopia: 3 Years of Follow-up. J Refract Surg. 2018;34(12):817-23. doi: 10.3928/1081597X-20181105-01 pmid: 30540364

Sachdev G, Ramamurthy D. Long-term safety of posterior chamber implantable phakic contact lens for the correction of myopia. Clin Ophthalmol. 2019;13:137-42. doi: 10.2147/OPTH.S185304 pmid: 30662257

Sarver EJ, Sanders DR, Vukich JA. Image quality in myopic eyes corrected with laser in situ keratomileusis and phakic intraocular lens. J Refract Surg. 2003;19(4):397-404. pmid: 12899469

Jimenez-Alfaro I, Benitez del Castillo JM, Garcia-Feijoo J, Gil de Bernabe JG, Serrano de La Iglesia JM. Safety of posterior chamber phakic intraocular lenses for the correction of high myopia: anterior segment changes after posterior chamber phakic intraocular lens implantation. Ophthalmology. 2001;108(1):90-9. pmid: 11150270

Senthil S, Choudhari NS, Vaddavalli PK, Murthy S, Reddy JC, Garudadri CS. Etiology and Management of Raised Intraocular Pressure following Posterior Chamber Phakic Intraocular Lens Implantation in Myopic Eyes. PLoS One. 2016;11(11):e0165469. doi: 10.1371/journal.pone.0165469 pmid: 27855172

Roberto BG. Phacoemulsification Cataract Surgery without Viscoelastic Substance. JOJ Ophthalmol. 2017;4(5). doi: 10.19080/jojo.2017.04.555646

Bianchi GR. Phacoemulsification Cataract Surgery without Viscoelastic Substance: Bianchi’s Method. Difficulties in Cataract Surgery. 5: Intech Open; 2018. p. 93-108.

Packer M. The Implantable Collamer Lens with a central port: review of the literature. Clin Ophthalmol. 2018;12:2427-38. doi: 10.2147/OPTH.S188785 pmid: 30568421

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