IVORC
  • Register
  • Login

Medical hypothesis discovery and innovation in ophthalmology

  1. Home
  2. Archives
  3. Vol. 10 No. 2 (2021): Summer 2021
  4. Articles

About the Journal

Editorial Team

Privacy Statement

Contact

Comparison of the efficacy of lotrafilcon B and comfilcon A silicone hydrogel bandage contact lenses after transepithelial photorefractive keratectomy

  • Nancy M. Lotfy
  • Tariq Alasbali
  • Abdulrahman M. Alsharif
  • Saeed M Al- Gehedan
  • Sabah Jastaneiah
  • Ashraf Al-Hazaimeh
  • Hiba Ali
  • Rajiv Khandekar

Medical hypothesis discovery and innovation in ophthalmology, Vol. 10 No. 2 (2021), 5 August 2021 , Page 43-49
https://doi.org/10.51329/mehdiophthal1420 Published 4 August 2021

  • View Article
  • Download
  • Share

Abstract

Background: At completion of transepithelial photorefractive keratectomy (t-PRK) surgery, the eye is usually fitted with a bandage contact lens to reduce discomfort and promote epithelial healing. This study aimed to compare the outcomes of eyes fitted with lotrafilcon B versus comfilcon A, silicone hydrogel bandage contact lenses after t-PRK for the correction of low to moderate myopia, with or without astigmatism.
Methods: In this comparative, prospective study, patients with myopia < -6 D with or without astigmatism (< 1.75 D), who underwent t-PRK between January and June 2018, were randomly allocated to the lotrafilcon B and comfilcon A groups. Preoperative characteristics, including age, sex, eye treated, uncorrected visual acuity (UCVA), best-corrected visual acuity, mesopic pupil size, central corneal thickness, and refractive error were recorded. Postoperatively, pain score, UCVA, and corneal epithelial defect size on days 1, 4, and 7 were compared between the two groups.
Results: Twenty-nine eyes were included in each group. Demographic characteristics and preoperative measurements were similar between the two groups. UCVA was significantly improved on day 7 as compared to day 1 in the comfilcon A group (P = 0.03), but remained the same in the lotrafilcon B group (P = 0.70) as on day 1 postoperatively. There was no significant difference in UCVA between the two groups at any follow-up visits (all P > 0.05). The pain score on the first postoperative day was significantly higher in the lotrafilcon B-fitted eyes than in the comfilcon A group (P < 0.001), but was significantly reduced in both groups compared to day 1 (both P < 0.001). The epithelial defect in the comfilcon A group was significantly greater than in the lotrafilcon B group (P < 0.001) at day 1 postoperatively, with significant improvement in both groups (both P < 0.001).
Conclusions: Healing responses were better with lotrafilcon B than with comfilcon A bandage contact lenses. The patients had a greater mean pain score with lotrafilcon B than with comfilcon A lenses on the first postoperative day, yet the final outcome was comparable between the two groups. We did not encounter any postoperative complications related to contact lens wear.
  • Full Text PDF
  • Abstract Viewed: 178 times
  • Full Text PDF Downloaded: 131 times

Download Statastics

  • Linkedin
  • Twitter
  • Facebook
  • Google Plus
  • Telegram
Open Journal Systems
Current Issue
  • Atom logo
  • RSS2 logo
  • RSS1 logo
Information
  • For Readers
  • For Authors
  • For Librarians
  • Home
  • Archives
  • Submissions
  • About the Journal
  • Editorial Team
  • Contact

ISSN: 2322-3219

This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.

© Copyright 2012-2022, CC BY-NC 4.0. All Rights Reserved.